FDA Recalls More than 7000 Bottles of Duloxetine

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prescription bottle tipped over with overflowing pills

The U.S. Food and Drug Administration (FDA) has announced a voluntary, manufacturer-initiated recall of more than 7,000 bottles of duloxetine delayed-release capsules due to unacceptable levels of a potential carcinogen.

Duloxetine (Cymbalta) is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat depression, anxiety, and some forms of long-term pain from fibromyalgia, chronic musculoskeletal pain, and neuropathic pain associated with diabetic peripheral neuropathy. Chronic pain and neuropathic pain may be caused by trauma and are sometimes seen in workers’ compensation claims.

The medication recall is due to the detection of elevated levels of the nitrosamine impurity, N-nitroso duloxetine. Nitrosamines are common in water and foods but exposure to nitrosamine impurities above acceptable levels and over long periods may increase cancer risk, the FDA reported.

The ongoing recall was initiated on October 10 by Breckenridge Pharmaceutical and covers 7107 bottles of 500-count, 20 mg duloxetine delayed-release capsules. The drug is manufactured by Towa Pharmaceutical Europe and distributed nationwide by BPI. The affected bottles are from lot number 220128 with an expiration date of 12/2024 and NDC of 51991-746-05.

MyMatrixx Response

MyMatrixx transaction records indicate that scripts for Duloxetine are low for our book of business. If you have any questions about this recall, please contact your MyMatrixx account team.